BH12 Granulomatous alopecia areata

Abstract A 46-year-old woman with Fitzpatrick skin type V presented sudden-onset accelerated diffuse hair loss. Her other relevant medical history included Graves disease. Trichoscopy showed black dots, broken hairs exclamation mark-like and yellow dots. She was provisionally diagnosed alopecia areata (AA). Laboratory work-up, including complete blood count, liver/renal parameters, antinuclear antibody complement screen did not reveal any abnormality. Thyroid function adjusted calcium level were all within the normal range. had slight iron, folate vitamin D deficiencies, which treated appropriate supplements. biopsy taken from scalp, histological examination a nonscarring process miniaturization, significant telogen shift peribulbar granulomatous inflammation. Subsequent syphilis serology negative, serum angiotensin-converting enzyme limits. No clinical features of sarcoidosis or observed. After careful clinicopathological correlation, she AA. We planned to treat her diphencyprone; however, grew back spontaneously after 2 months. AA is loss that can commonly affect scalp beard, as well hair-bearing surface on body. It T-cell-mediated disease characteristic features, lymphocytic inflammation without eosinophils, follicular miniaturization an increase in catagen/telogen hairs. Peribulbar rare histopathological finding In context alopecia, conditions associated findings include sarcoidosis, various forms inflammatory cicatrizing alopecia. To our knowledge, only five cases have been reported. Notably, we describe first case UK second internationally show spontaneous resolution, suggesting prognosis dissimilar histologically typical summarize, described clinically atypical findings. Granulomatous should preclude diagnosis This demonstrates importance correlation histopathology could potentially be misleading.